Unlock the Genetics of Ischemic Stroke Comorbidity

A recent study conducted by the Rajiv Gandhi Centre for Biotechnology ( RGCB ) has revealed that genetic factors of different ethnic groups and regional disparities in comorbidities play a crucial role in influencing the burden of stroke . The study , conducted by researcher Moinak Banerjee , highlighted that the underlying genetic factors determine regional variations , which in turn can define the burden of stroke . The study , published in the biomedical publication eLife , emphasized that while metabolic risk is a major driver for stroke in America and Europe , vascular risk is the main cause of stroke incidence in Asian and African regions.

The research covered data from 204 countries collected from 2009 - 2019 for stroke and its major comorbid risks . The study examined a total of eleven diseases , including overall stroke , Ischemic Stroke ( IS ) , intracranial haemorrhage ( ICH ) , along with comorbid factors like ischemic heart disease ( IHD ) , diabetes type 1 & type 2 , chronic kidney disease , high blood pressure , high body mass index ( BMI ) , and high LDL cholesterol . Strokes affected over 101 million people globally and caused over 6.55 million deaths in 2019 , making it one of the leading causes of mortality.

The findings of the study indicate that comorbidities in stroke can amplify the risk of stroke and its outcome , underscoring the need for effective prevention and management strategies . Director of RGCB , Chandrabhas Narayana , mentioned that the study provides a population perspective on stroke prevention and management , which is crucial for policy - makers to address regional disparities and ethnic and region - specific genetic factors . The study challenges the traditional approach of viewing stroke burdens solely from a socio - economic perspective and highlights the importance of understanding genetic factors in shaping prevention strategies.

The study aims to assist health policymakers in prioritizing the management of underlying comorbid factors to alleviate their impact on stroke burdens . By understanding the epidemiological observations of major conditions and their comorbidities from a genetic viewpoint , policymakers can better plan programs to reduce the burden of comorbidities and ultimately , the burden of stroke . The research provides valuable insights into the prevention and management of strokes and serves as a significant contribution to the field of genetics and stroke research.