Time: 2024-12-17
identify form of refractive mistake in inherit retinene disease may better management and cognition of familial association with refractive mistake. understanding the familial factor and refractive mistake form associate with inherit retinene disease may lead to better patient result, harmonize to findings print in the American Journal of Ophthalmology.
refractive mistake complicate IRD vision problem as the research team retrospectively review the chart of patient with IRD treat at three survey site. The analysis include 634 participant with a mean age of 34.7, of which More than one-half were work_force. Overall, nearly one-half of the survey population have rod-cone muscular_dystrophy as the most park phenotype, while USH2A was the most park gene found in 10.3% of patients.
After analyze disease phenotype, genotype, best-correct ocular acuity, refraction, and demographic data, the research_worker found that NYX was associate with the high spherical equivalent refractive mistake of myopia, follow by IMPG2 and RPGR. For gene associate with hyperopia, BEST1 have the high spherical equivalent refractive mistake, follow by RS1 and CNGA3.
Dr. Borooah and colleague compare pediatric, young adult, and aged adult patient to a general population and found significant difference in the prevalence of myopia and hyperopia across different age group. survey participant 3-10 old_age old have a higher prevalence of high myopia and high hyperopia than schoolchildren in the general population, while those 43 old_age old and aged were more nearsighted than the general population in the Beaver Dam study.
Dr. Borooah and colleague recommend hanker-term follow-up of patient with myopia and timely treatment of blind comorbidities. In IRDs associate with hyperopia, screening for short axial length and hazard of angle closing glaucoma could be perform. It may now be possible to prevent the progression of refractive mistake in gene associate with myopia with pharmaceutical agent such as low-dose atropine eye drops.
In decision, understanding familial association with refractive mistake in inherit retinene disease can significantly impact patient management and result. foster research in this area is crucial for better the understanding and treatment of these complex conditions.