Time: 2024-09-14
The response to biologics for asthma can change depend on different result . The survey print in The Journal of Allergy and Clinical Immunology : In Practice foreground the standard for response , which include a 50 % or greater decrease in aggravation rate and daily hanker - term oral corticosteroid dose . patient with more significant damage before start biological treatment for asthma generally have better response across all outcomes.
The survey include data from 2,210 patient from 21 state , with a majority being White woman with a median age of 55 old_age and a history of asthma for 20 old_age . Before treatment , patient have elevated_railway blood eosinophil count and were classified_ad as have type 2 - high disease . The response to treatment were measure establish on decrease in aggravation rate , hanker - term oral corticosteroid dose , improvement in asthma control , and lung function.
The research_worker found that 80.7 % of patient have a 50 % or greater decrease in aggravation , while 44.3 % have a similar decrease in daily corticosteroid dose . Additionally , 51.1 % show improvement in asthma control , and 53.6 % have an improvement of 100 milliliter or More in FEV1 . patient who achieve response in multiple sphere change across different class of biologics.
The survey also foreground association between patient feature and response to treatment . factor such as lower_berth daily corticosteroid dose , absence of particular conditions like osteoporosis , and a history of atopic dermatitis were associate to better response rates . The research_worker stress the complexity of response and the need for caution when interpretation data across studies.
In decision , the survey stress the importance of personalize treatment goal and pull_off patient expectation see biological therapy for asthma . By predict person response to treatment , doctor can tailor intervention to optimize result for patient with asthma . asthma treatment with biologics present a alone opportunity to better patient result , but understanding the variability in response is crucial for effective management.