Tips for Healthy Brain: Novel Treatment for Traumatic Brain Injury and Neurodegenerative Disease - Health

novel treatment for traumatic Brain Injury and Neurodegenerative Disease

University Hospitals and Case Western Reserve University research team has report a discovery in treat Traumatic brain injury ( TBI ) that prevent the progression to chronic neurodegeneration . harmonize to estimate , there are about 5 million people in the U.S. life with chronic neurodegeneration due to TBI . The lack of understanding of why acute_accent TBI passage into chronic neurodegeneration has impede the development of treatment option . However , a Holocene survey print in Cell Reports Medicine by research_worker at University Hospitals ( UH ) and Case Western Reserve University has shed light on this issue.

 brief P110 treatment during the acute_accent time time_period after TBI permanently normalize mitochondrial fission / fusion and prevent subsequent injury to the brain , include oxidative damage , blood - brain barrier deterioration , axonal degeneration , and cognitive damage , 17 calendar_month later . This is equivalent to many decade in people , explain Andrew A. Pieper , senior writer of the study

. The survey uncover that excessive mitochondrial fission could be reduce pharmacologically with a small peptide agent name P110 , which block the interaction of cellular protein Fis1 and Drp1 . The research has show promise consequence in protect the brain from hanker - term damage post - TBI.

nutritional intervention and remedy benefit Post - TBI

research_worker from Australia and the United States have review literature on potential remedy benefit post - TBI through nutritional intervention . The Centers for Disease Control and Prevention report a nearly 53 % addition in traumatic brain injury - associate emergency department visit , hospitalization , and death in the United States since the previous decade . TBIs interrupt the convention operation of the brain and can lead to assorted physical , neurological , and emotional damage.

The use of particular nutritional addendum has show promise consequence in extenuate the effects of TBIs . compound like omega-3_fatty_acid fatso acid , magnesium , and anthocyanins have been identify as potential neuroprotective agent against the brain 's inflammatory response post - TBI . other addendum such as creatine monohydrate , choline , and melatonin have also been analyze for their benefit in address TBI - associate symptom and complications.

prevention and treatment scheme for traumatic Brain Injury

prevention scheme and neuroprotective therapy are crucial in minimize the happening and badness of TBIs . particular supplement and dietary regimen target inflammation and oxidative stress can rich_person beneficial effects before and after TBI . The link between TBI and later neurodegenerative conditions has been increasingly acknowledge , highlight the importance of address TBIs to reduce the hazard of cognitive decline and neurodegenerative disorders.

In decision , the latest research on TBI treatment and prevention scheme offer hope for better result for person with TBI and reduction the hanker - term impact of neurodegenerative disease . foster survey and clinical test on advanced treatment and nutritional intervention are necessity in advance the field of TBI research and better patient care.