Time: 2024-09-10
In Holocene research show at the ESC Congress 2024 , two test involve frail aged patient found that there be no clinical benefit in pickings Blood pressure - lowering medicine in the evening compare to the morning . The BedMed test , which include Canadian patient without glaucoma , and the BedMed - Frail test , which concentrate on patient in Canadian hanker - term care facility , both aim to determine if the timing of medicine administration affect major health problem such as death , stroke , heart attack , or heart failure . secondary goal include analyze unexpected hospital visit , vision issue , cognitive function , and fractures.
The BedMed test involve 3,357 adult with an average age of 67 old_age , while the BedMed - Frail test have 776 participant with an average age of 88 old_age . consequence show that there be no difference in safety result , rates of hospitalization , or emergency department visit between those who take their medicine at bedtime versus in the morning . major health problem happen in a similar percentage of patient regardless of the timing of medicine administration , bespeak that there be no significant difference in result between the groups.
Two new test , the BedMed and BedMed - Frail test , show at the ESC Congress , further confirm that the time of day does not matter when it semen to pickings antihypertensive medicine . These test , conduct in Canada , show no difference in death or cardiovascular event between patient pickings their antihypertensive medicine at night versus in the morning . lead research_worker Scott Garrison , MD , PhD , state that the benefit and hazard of antihypertensive medicine do not change with the time of day they are use , settling the issue that has been a subject of argument in Holocene years.
The primary result of both test were death or hospitalization for acute_accent coronary_thrombosis syndrome , stroke , or heart failure . consequence bespeak that there Washington no injury , but also no benefit , of pickings antihypertensive at bedtime compare to in the morning . These findings , along with previous test such as the 2010 MAPEC test and the 2019 Hygia Chronotherapy Trial , supply evidence that the timing of antihypertensive medicine administration does not impact its efficacy in reduction cardiovascular events.
In decision , the consequence of these test propose that people should return their antihypertensive medicine at a time that best suit them , without concern for the time of day . While some medicine may rich_person timing - associate side effects , the overall efficacy of antihypertensive treatment remains consistent regardless of when the medicine is take . With multiple test now screening similar consequence , the argument see the timing of antihypertensive medicine administration can be put_option to remainder , let patient to focus on what plant best for their person needs.
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