Prevent Fatty Liver Disease in Spinal Muscular Atrophy Patients with Healthy Habits - Health

Spinal Muscular Atrophy Patients at Risk of Fatty Liver Disease

An international study has revealed that individuals living with Spinal Muscular Atrophy ( SMA ) may be at a higher risk of developing fatty Liver disease , indicating potential additional health issues for SMA patients . SMA is a rare genetic condition that affects the production of Survival Motor Neuron ( SMN ) , crucial for nerve function . The study , involving researchers from the US , Singapore , and Scotland , noted that the impact of SMA extends beyond the nervous system , potentially affecting organs like the liver.

Prevent Fatty Liver Disease in Spinal Muscular Atrophy Patients with Healthy Habits

Fatty liver disease , typically associated with heart conditions , diabetes , and obesity , is a condition characterized by fat accumulation in the liver , leading to inflammation and damage . The presence of this condition in SMA patients , even in children as young as three years old , raises significant concerns due to its long - term consequences on health.

 The genetic mutation responsible for SMA reduces SMN protein levels in liver cells , impacting their ability to process fat effectively . Editing the faulty gene in patients ' stem cells to boost SMN production reversed the liver dysfunction caused by the mutation . This demonstrates a direct link between the genetic defect and liver issues in SMA.

Dr. Crystal Yeo , the director of the research and a Clinician - Scientist , emphasized the importance of understanding the potential health risks faced by SMA patients over time . Prof Basil Darras , Chief of the Division of Clinical Neurology at Boston Children 's Hospital , highlighted the need to monitor and treat SMA patients differently as they live longer.

Cholera Outbreak Prompts Hygiene Advisory

In light of a cholera outbreak in Kerala and Gujarat , medical experts stress the importance of maintaining hygiene to prevent the spread of the waterborne bacterial infection . Cholera , caused by Vibrio cholerae bacteria , results in severe watery diarrhea and dehydration , posing a risk to vulnerable populations like children and the elderly.

Dr. Sujatha Thyagarajan , a senior consultant in Pediatrics , underscores the significance of hygiene practices and access to clean water to prevent cholera transmission . The outbreak in Kerala 's capital , Thiruvananthapuram , and cases in Gujarat highlight the urgency of containing the spread through surveillance and prevention measures.

 The rapid loss of fluids and electrolytes in cholera can be life - threatening if not promptly replaced . Ensuring proper sanitation practices , access to clean water , and maintaining personal hygiene are crucial steps in preventing cholera outbreaks.

Dr. Thyagarajan recommends timely rehydration through oral or intravenous solutions and emphasizes the role of antibiotics in severe cases . Awareness campaigns and active surveillance are essential in managing and preventing cholera outbreaks , underscoring the importance of public health initiatives in curbing infectious diseases.